DXT by RESPINOR:
Revolutionizing Diaphragm Monitoring for Critical Care

RESPINOR's DXT is a novel, non-invasive ultrasound-based medical device. Applicable in critical care for accurate and continuous diaphragm monitoring for early detection of diaphragm dysfunction. Secured substantial funding from H2020 and The Research Council of Norway. Successfully completed clinical evidence studies for the first patient segment, mechanical ventilation (MV). RESPNOR is EN ISO 13485:2016 certified and working towards marketing authorization in both EU and the US. DXT offers a huge market potential with >350m patients in US/EU. We aim to become the technology of choice for assessing work of breathing.

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What is DXT?

DXT, or Diaphragm Excursion Technology, is a groundbreaking non-invasive medical device developed by RESPINOR that utilizes ultrasound for operator-independent, continuous monitoring of the diaphragm, the main breathing muscle, in critically ill patients. This technology aids in the early detection of diaphragm dysfunction and enhances clinical decision-making in critical care settings.

Product: RESPINOR DXT is a medical technology designed to provide an objective measure of diaphragm function.
Purpose: DXT aims to optimize extubation timing, reduce re-intubation rates, improve patient outcomes, and thereby lower healthcare costs.
Technology: DXT uses sensors with optimized design for patient comfort, continuous monitoring, and computer-aided sensor placement.
Non-Invasive: DXT offers a non-invasive solution for monitoring diaphragm function.
Clinically proven output: DXT measures diaphragm excursion (DE) and respiratory rate (RR) in real-time including trends. DXT has a well-established cut-off value to detect patients at increased risk of reintubation during the weaning process from MV.
Medical Need: By identifying patients at increased risk of extubation failure during the weaning process from mechanical ventilation, RESPINOR DXT has the potential to improve decision making and reduce the number of emergency re-intubations, and potential morbidity associated with mechanical ventilation, as well as ICU and hospital length of stay. 
Good safety profile: a total of 389 patients been monitored with DXT through the clinical development, and no serious adverse device effects have been reported.
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Recent updates from RESPINOR

July 16, 2024

Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study, Demoule et al. Critical Care (2024) 28:245.

RESPINOR has successfully completed the clinical evidence program for the first indication, weaning from mechanical ventilation (MV), and is now preparing for regulatory submission both in Europe and the US.
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July 21, 2023

RESPINOR announces new Chair of the Board

On July 21, 2023, RESPINOR AS, a clinical-stage medical device company, appointed Anders Wold as Chair of the Board, effective immediately. Wold brings four decades of healthcare and ultrasound industry leadership to the role, having previously served as President and CEO of GE Healthcare Clinical Care Solutions. The current Chair, Aage Bryn, will become a Board member, while the rest of the Board will maintain their positions. Wold's expertise in the ultrasound business and international MedTech connections will support RESPINOR in commercializing and launching their innovative DXT product. Wold expressed enthusiasm for joining RESPINOR and looks forward to addressing unmet clinical needs in respiratory care.
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December 9, 2022

First patient included in the multicenter, multinational DE-RISK WF II study in Europe

The first patient has been successfully included in the DE-RISK WF II study at the coordinating center, Hôpitaux Universitaires Pitié Salpêtrière, in Paris.
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January 4, 2022

RESPINOR is strengthening the team preparing for commercialization of DXT

Meet Magdalena K. Gjefle, our new Director of Business Development, and Tristan Hollande, our CTO at RESPINOR. Magdalena, with 30 years of experience in business development, finance, and the pharma/biotech sector, holds advanced degrees from prestigious institutions. She's joined us from Inven2 and Weifa. Tristan, an engineer with over two decades of experience in sensor measurements, maps, and GPS-related software, has successfully led R&D projects. Visit their LinkedIn profiles for more information.
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October 15, 2021

RESPINOR AS Successfully completed Private Placement of approx. NOK 20 million (€ 2,0 million)

The Company's Board of Directors is pleased to announce the successful completion of a Private Placement, led by our financial advisor, Corpura Fondkommission AB, raising approximately NOK 20 million (€2.0 million) in gross proceeds. These funds will support the ongoing clinical study DE-RISK WF in France, Italy, and Norway, as well as the continued development of the DXT product, aiming for a design freeze and CE mark submission for a Q4-2022 product launch. We are also partnering with Corpura Fondkommission for our financial advisory needs and plan to list the Company's shares on a Swedish stock exchange in early 2022.
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RESPINOR: MedTech innovator specializing in diaphragm monitoring, introducing DXT, a non-invasive ultrasound-based technology to improve critical care and outcomes.

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